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Cancer: Breast Cancer Article Category - Page 3 Tamoxifen is a drug that interferes with the activity of estrogen particularly in the mammary glands of women. It has been used to treat and prevent breast cancer for the past 3 decades. Breast cancer cells needs estrogen to grow. Without estrogen these cells are deprived of their vital nutrition and may die. This principle is used when Tamoxifen drug was formulated. Tamoxifen binds with the estrogen receptors in the breast thereby depriving breast cancer cells of vital protein in estrogen. To put it in layman's terms imagine an auditorium with a limited number of seats and assume the auditorium manager gives advance information to all the well behaved people and books their tickets. The auditorium gets filled with all the good guys the unruly bad elements who come late do not get a place inside. The show in the auditorium goes on without any trouble or untoward events. In this case the good guys are the molecules in the Tamoxifen which bind to estrogen receptors and the bad elements are the breast cancer cells. This process is also known as competitive antagonism.

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